Revised guidelines for the diagnosis and management of hairy cell leukaemia and hairy cell leukaemia variant*.
نویسندگان
چکیده
The British Committee for Standards in Haematology first produced guidelines for the diagnosis and management of hairy cell leukaemia and hairy cell leukaemia variant in 2000. This revision updates those guidelines and covers the areas of diagnosis, treatment and assessment of response to therapy.
منابع مشابه
Hairy cell leukemia-variant.
Hairy cell leukaemia variant is a very rare chronic lymphoproliferative disorder and is closely related to hairy cell leukemia. We hereby describe a case of hairy cell leukaemia variant for the first time in Saudi Arabia. An elderly Saudi man presented with pallor, massive splenomegaly, and moderate hepatomegaly. Hemoglobin was 7.7 g/dl, Platelets were 134 x109/l and white blood count was 140x1...
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Hairy cell leukaemia is a rare form of lymphoproliferative disease that affects 2% of leukaemia patients and was first described in 1958 as leukaemic reticuloendotheliosis. The typical presentation is pancytopenia, splenomegaly and abnormal lymphoid cells in blood with hairy cytoplasmic projections. The pathological hairy cell resembles in many ways B-lymphocyte as in chronic lymphocytic leukae...
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Hairy cell leukaemia is a rare condition and the patient reported here is only the third such case out of 527 patients with all types of leukaemia seen at our hospital over the last 4 years. A second malignancy in a patient with hairy cell leukaemia has been documented in detail only once before (Adler, Shetty and Golomb, 1979). The association of Kaposi's sarcoma, a common tumour in parts of s...
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Occurrences of second malignancies in hairy cell leukaemia are well recognised. Most of these malignancies are either solid tumours or lymphoproliferative disorders. The association of myeloproliferative disorders with hairy cell leukaemia (HCL) is very rare. This report describes a case of a patient with HCL who after remaining in remission developed Philadelphia chromosome positive chronic my...
متن کاملHairy-cell leukaemia in a renal transplant recipient.
Hairy-cell leukaemia is a rather uncommon chronic malignant lymphoproliferative disorder accounting for about 2% of all adult leukaemia cases [1]. This clonal B-cell proliferation [2] is characterized by a cellular infiltration of both bone marrow and spleen by large differentiated B cells, often exhibiting hair-like protrusions (hairy cells). We report here the first case of hairy-cell leukaem...
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ورودعنوان ژورنال:
- British journal of haematology
دوره 156 2 شماره
صفحات -
تاریخ انتشار 2012